Valproate-associated Hyperammonemic Encephalopathy
نویسندگان
چکیده
منابع مشابه
Valproate-associated hyperammonemic encephalopathy.
The use of valproic acid (VPA) (also known as Depakote, Depakene, and others) frequently results in elevated plasma ammonia. In some people, hyperammonemia may be clinically significant, resulting in hyperammonemic encephalopathy, which may be severe. Valproic acid-induced hyperammonemic encephalopathy may occur in people with normal liver function, despite normal doses and serum levels of VPA....
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Valproate is the best choice drug for a variety of medical conditions. As with any other drug, it has adverse effects, and it is important to emphasize the possibility of those adverse effects to prevent complications. We present the case history of a 44-year-old male with valproate-induced hyperammonemic encephalopathy, despite having normal liver function tests. This case includes a detailed ...
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A 21-year-old male known case of primary hypothyroidism, Seizure disorder sequelae of an old trauma receiving sodium valproate, clobazam and phenobarbitone for control of Generalized tonic clonic seizures reported to neurology OPD with history of altered sensorium and gait unsteadiness for 1 week with history of hike in valproate dose 2 weeks before. On examination he was drowsy. Neurological e...
متن کامل[Valproate-induced hyperammonemic encephalopathy].
Encefalopatia hiperamonemica inducida por acido valproico.
متن کاملValproate induced hyperammonemic encephalopathy treated by haemodialysis
Valproate (VPA)-induced hyperammonemic encephalopathy is an unusual, but serious, adverse effect of divalproex sodium (DVPX) treatment and if untreated can lead to raised intracranial pressure, seizures, coma, and eventually death. It can, however, be reversed if an early diagnosis is made. It is therefore extremely important to recognize it and discontinue DVPX treatment. Our patient developed...
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ژورنال
عنوان ژورنال: The Journal of the American Board of Family Medicine
سال: 2007
ISSN: 1557-2625,1558-7118
DOI: 10.3122/jabfm.2007.05.070062